发明名称 |
[4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-(4-BROMO-3-METHYL-5-PROPOXY-THIOPHEN-2-YL)-METHANONE HYDROCHLORIDE AS AN INHIBITOR OFMAST CELL TRYPTASE |
摘要 |
The present invention extends to the compound of formula I, or a prodrug, pharmaceutically acceptable salt, or solvate of said compound. Furthermore, the present invention is directed to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed to the use of a compound of formula I as an inhibitor of tryptase, comprising introducing the compound into a composition comprising tryptase. In addition, the present invention is directed to the use of a compound of formula I for treating a patient suffering from, or subject to, a physiological condition in need of amelioration of an inhibitor of tryptase comprising administering to the patient a therapeutically effective amount o f the compound of Claim 1. The present invention is directed also to the preparation of a compound of formula I.
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申请公布号 |
CA2560649(A1) |
申请公布日期 |
2005.10.20 |
申请号 |
CA20052560649 |
申请日期 |
2005.03.24 |
申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
HADDAD, EL-BDAOUI;SLEDESKI, ADAM W.;CZEKAJ, MARK;GAO, ZHONGLI;LEVELL, JULIAN;DAVIS, LARRY |
分类号 |
C07D409/06;A61K31/4535;A61P11/06 |
主分类号 |
C07D409/06 |
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