| 发明名称 |
ADMINISTRACAO IONTOFORETICA DE ROTIGOTINA PARA O TRATAMENTO DA DOENCA DE PARKINSON |
| 摘要 |
<p>By using a composition comprising rotigotine and at least one chloride salt in a concentration of 1 to 140 mmol/l, the composition having a pH of 4 to 6.5 in a iontophoretic device for the treatment of Parkinson's disease, it became possible to obtain a rotigotine flux across the human stratum corneum which was higher than the one previously obtained with conventional passive diffusion systems.</p> |
| 申请公布号 |
PT1426049(E) |
申请公布日期 |
2005.09.30 |
| 申请号 |
PT20020026871T |
申请日期 |
2002.12.02 |
| 申请人 |
SCHWARZ PHARMA AG |
发明人 |
JOHANNA AALTJE BOUWSTRA;HANS-MICHAEL WOLFF;GAI LING LI;AKHMAD KHARIS NUGROHO |
| 分类号 |
A61K9/00;A61K31/381;A61K47/00;(IPC1-7):A61K31/381;A61P25/16 |
主分类号 |
A61K9/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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