发明名称 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH
摘要 The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R<1>, R<2>, R<3>, R<4>, R<5>, n, A and B are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders, which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
申请公布号 EP1578732(A2) 申请公布日期 2005.09.28
申请号 EP20030780443 申请日期 2003.12.17
申请人 PFIZER PRODUCTS INC. 发明人 KATH, JOHN CHARLES;LUZZIO, MICHAEL, JOSEPH
分类号 C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D513/04;(IPC1-7):C07D239/00 主分类号 C07D401/14
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