NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2)

摘要

A compound of the following general formula or its salt or a hydrate thereof exhibits excellent hepatocyte growth factor receptor (HGFR) inhibiting activity and provides a compound having antitumor activity, vascularization inhibiting activity or cancer metastasis inhibiting activity or its salt or a hydrate thereof. (wherein R<1> represents a C1-C6 alkyl, etc.; each of R<2> and R<3> represents a hydrogen atom; R<4>, R<5>, R<6> and R<7> may be identical with or different from each other and each represent a hydrogen atom, a halogen atom, a C1-C6 alkyl, etc.; R<8> represents a hydrogen atom, etc.; R<9b> represents a 3 to 10-membered nonaromatic heterocyclic group, etc.; V<1> represents an oxygen atom, etc.; V<2> represents an oxygen atom or a sulfur atom; W represents a group of the formula -CH2-, etc.; X represents a group of the formula -CH=, a nitrogen atom, etc.; and Y represents an oxygen atom, etc.).