发明名称 |
MULTILAYER DOSAGE FORMS, WHICH CONTAIN ACTIVE SUBSTANCES AND WHICH COMPRISE A NEUTRAL CORE, AND AN INNER AND OUTER COATING CONSISTING OF METHACRYLATE COPOLYMERS AND METHACRYLATE MONOMERS |
摘要 |
The invention relates to a multilayer dosage form comprised of: a) a neutral core; b) an inner coating consisting of a methacrylate copolymer; c) an outer coating consisting of a copolymer of which 40 to 95 % by weight is composed of radically polymerized C1 to C4 alkyl esters of acrylic acid or of methacrylic acid and of which 5 to 60 % by weight is composed of (meth)acrylate monomers having an anionic group in the alkyl radical. The invention is characterized in that the inner coating is essentially comprised of a methacrylate copolymer, of which at least up to 90 % by weight consists of (meth)acrylate monomers with neutral radicals, which, in accordance with DIN 53 787, has a minimum film formation temperature of no higher than 30 °C, and which contains the pharmaceutical active substance in bound form.
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申请公布号 |
KR20050083847(A) |
申请公布日期 |
2005.08.26 |
申请号 |
KR20057007384 |
申请日期 |
2005.04.28 |
申请人 |
ROHM GMBH & CO. KG |
发明人 |
PETEREIT HANS ULRICH;RUDOLPH MARKUS;DRESSMAN JENNIFER;BECKERT THOMAS |
分类号 |
A61K9/16;A61K9/20;A61K9/28;A61K9/50;A61K31/58;(IPC1-7):A61K9/32;A61K31/57 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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