NEUES VERFAHREN ZUR HERSTELLUNG VON ALPHA-(2,4-DISULPHOPHENYL)-N-TERT-BUTYLNITRON UND SEINE PHARMAZEUTISCH AKZEPTABLEN SALZE
摘要
An integrated process for preparing alpha-(2,4-disulfophenyl)-N-tert-butylnitrone and its salts is disclosed in which N-tert-butylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutralisation product is condensed with an appropriate aldehyde.
申请公布号
DE60104649(T2)
申请公布日期
2005.08.11
申请号
DE2001604649T
申请日期
2001.01.04
申请人
ASTRAZENECA AB, SOEDERTAELJE;RENOVIS, INC.
发明人
BLIXT, JOERGEN;KRUK, HENRY;LARSSON, ULF;MCGINLEY, JOHN;POUHOV, SERGEI;VAJDA, JOHN;WILCOX, ALLAN
