| 发明名称 |
Macrolide analogs |
| 摘要 |
Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
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| 申请公布号 |
US6927057(B2) |
申请公布日期 |
2005.08.09 |
| 申请号 |
US20010859854 |
申请日期 |
2001.05.16 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
KHOSLA CHAITAN;ASHLEY GARY;KAO CAMILLA M.;MCDANIEL ROBERT |
| 分类号 |
C07B61/00;C07D309/36;C07D311/92;C07D323/00;C07D407/06;C07H17/08;C12N9/00;C12N15/52;C12P7/26;C12P17/06;C12P17/16;(IPC1-7):C12N9/00;C12P1/00 |
主分类号 |
C07B61/00 |
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