发明名称 |
System and method for detecting bioanalytes and method for producing a bioanalyte sensor |
摘要 |
The present invention discloses an indicator protein, and a method for making such a fusion protien, having a first binding moiety having a binding domain specific for a class of analytes that undergoes a reproducible allosteric change in conformation when said analytes are reversibly bound; a second moiety and third moiety that are covalently linked to either side of the first binding moiety such that the second and third moieties undergo a change in relative position when an analyte of interest molecule binds to the binding moiety; and the second and third moieties undergo a change in optical properties when their relative positions change and that change can be monitored remotely by optical means. The present invention also discloses a system and method for detecting glucose that uses such a fusion protein in a variety of formats including a subcutaneously and in a bioreactor.
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申请公布号 |
US2005118726(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
US20030649433 |
申请日期 |
2003.08.26 |
申请人 |
SCHULTZ JEROME S.;YI KAIMING |
发明人 |
SCHULTZ JEROME S.;YI KAIMING |
分类号 |
G01N33/543;G01N33/58;G01N33/66;(IPC1-7):G01N33/543 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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