发明名称 |
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN- COUPLED RECEPTOR 77 (GPR77) |
摘要 |
<p>The invention provides a human GPR77 which is associated with the cardiovascular disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of GPR77 as well as pharmaceutical compositions comprising such compounds.</p> |
申请公布号 |
WO2005050199(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
WO2004EP11806 |
申请日期 |
2004.10.19 |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;SUMMER, HOLGER |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;SUMMER, HOLGER |
分类号 |
C12Q1/68;G01N33/50;G01N33/566;G01N33/574;G01N33/68;(IPC1-7):G01N33/50;A61K38/00;A61K39/395;A61K48/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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