DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH ORGANIC CATION TRANSPORTER SLC22A9 (SLC22A9)

摘要

The invention provides a human SLC22A9 which is associated with the gastroenterological diseases, cardiovascular diseaes, metabolic diseases, cancer, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of gastroenterological diseases, cardiovascular diseaes, metabolic diseases, cancer, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of SLC22A9 as well as pharmaceutical compositions comprising such compounds.