发明名称 COMPOSITIONS AND METHODS FOR REDUCING THE RISK OF EPILEPTIC OCCURRENCE AND/OR FOR TREATMENT OF SEIZURE DISORDERS
摘要 The present invention relates to compounds and compositions useful for reducing the risk of epileptic occurrences and/or for alleviating epileptic phenomena in patients. In accordance with the invention, the compounds and compositions have at least the following two components: a) vitamin B6-based component selected from pyridoxal, pyridoxamine, pyridoxine, their pharmaceutically acceptable functional derivatives and salts; and b) at least one antiepileptic drug (AED) or anticonvulsive, neuroprotective drug or nootrope compound or moiety. The invention further relates to methods for preventing epileptic episodes and for alleviating epileptic episodes, as well as methods for reducing side effects of antiepileptic drugs.
申请公布号 WO2005016228(A3) 申请公布日期 2005.05.19
申请号 WO2004IL00745 申请日期 2004.08.12
申请人 D-PHARM LTD.;ADVANCED NEUROPROTECTIVE SYSTEMS LTD.;DOLINA, SVETLANA;SHTEIMAN, VITALY;VINNIKOVA, MARINA;SHAPIRO, ISRAEL 发明人 DOLINA, SVETLANA;SHTEIMAN, VITALY;VINNIKOVA, MARINA;SHAPIRO, ISRAEL
分类号 A61K;A61K31/44;A61P25/08;C07D;C07D213/02 主分类号 A61K
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