| 发明名称 |
Phenylalanine enamide derivatives |
| 摘要 |
Phenylalanine enamide derivatives of formula (1) are described:
wherein R 1 , R x , R y , R z , X and V are as defined in claim 1.
The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells. |
| 申请公布号 |
GB2387845(B) |
申请公布日期 |
2005.05.11 |
| 申请号 |
GB20030018429 |
申请日期 |
2002.01.18 |
| 申请人 |
* CELLTECH R & D LIMITED |
发明人 |
STUART * BAILEY;JULIEN ALISTAIR * BROWN;STEPHEN * BRAND;JAMES ANDREW * JOHNSON;JOHN ROBERT * PORTER;JOHN CLIFFORD * HEAD |
| 分类号 |
A61K31/198;A61K31/4375;A61K31/44;A61K31/4406;A61K31/497;A61P3/10;A61P9/00;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P37/00;A61P37/06;A61P43/00;C07C229/34;C07C229/46;C07C233/82;C07C321/22;C07C323/30;C07D213/81;C07D213/89;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D471/04;(IPC1-7):C07D213/81;C07C229/36 |
主分类号 |
A61K31/198 |
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