СПОСОБ ПРОГНОЗИРОВАНИЯ ИСХОДОВ ОСТРОГО ВИРУСНОГО ГЕПАТИТА С

摘要

FIELD: medicine, clinical virology. ^ SUBSTANCE: method involves assay of antibodies raised against some antigen sites of two surface proteins (E1 and E2) by using the following 5 synthetic peptides as antigens: 1) NH2-SGHRMAWDMMMNWSP-CONH2; 2) NH2-STLTSLPTPGASG-CONH2; 3) NH2-RPYAWHYAPRPAGIVPASQV-CONH2; 4) NH-TTDRIFGAPTYSWGENETDVL-CONH2; 5) NH2-TWIMNSTGFTKTAGGPPANIGGVGNNT-CONH2. The favorable finish of disease is prognosticated by detection of antibodies for the first 3-4 weeks of disease. The advantage of the invention involves the prognosis for the disease finish in the early stage of disease. Invention can be used in clinics of infectious diseases for aims of early prognosis of acute hepatitis C finish. ^ EFFECT: improved method for prognosis of hepatitis C. ^ 6 tbl, 3 ex