发明名称 |
Binding assays that use the T1R1/T1R3 (Umami) taste receptor to identify compounds that elicit or modulate umami taste |
摘要 |
Binding assays for identifying compounds that induce or modulate the T1R1/T1R3 (umami) receptor-associated taste are provided. These binding assays detect the specific binding of a compound to a T1R1/T1R3 (umami) taste receptor or detect the modulation (inhibition or enhancement) of the binding of another compound, e.g., L-glutamate, L-aspartate or lactisole to a T1R1/T1R3 umami taste receptor. Compounds that are identified in these binding assays have potential application as T1R1/T1R3 umami taste modulators and therefore can be used as flavor additives in compositions for human or animal consumption.
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申请公布号 |
US2005084932(A1) |
申请公布日期 |
2005.04.21 |
申请号 |
US20030725418 |
申请日期 |
2003.12.03 |
申请人 |
SENOMYX, INC. |
发明人 |
ZOLLER MARK;LI XIAODONG;STASZEWSKI LENA;O'CONNELL SHAWN;ZOZULYA SERGEY;ADLER JON E.;XU HONG;ECHEVERRI FERNANDO |
分类号 |
C07K14/705;(IPC1-7):A61K38/17;C07H21/04 |
主分类号 |
C07K14/705 |
代理机构 |
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主权项 |
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