| 发明名称 |
TETRAHYDROPYRANYL CYCLOPENTYL HETEROCYLIC AMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY |
| 摘要 |
The present invention is directed to compounds of the formula (I) Wherein A, B, D, X, Y, n, R<1>, R<3>, R<4>, R<5>, R<15>, R<16>, R<17>, R<18> and the dashed line are as defined herein which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2. |
| 申请公布号 |
WO2004082616(A3) |
申请公布日期 |
2005.04.21 |
| 申请号 |
WO2004US07831 |
申请日期 |
2004.03.12 |
| 申请人 |
MERCK & CO. INC.;GOBLE, STEPHEN, D.;PASTERNAK, ALEXANDER;MILLS, SANDER, G.;ZHOU, CHANGYOU;YANG, LIHU |
发明人 |
GOBLE, STEPHEN, D.;PASTERNAK, ALEXANDER;MILLS, SANDER, G.;ZHOU, CHANGYOU;YANG, LIHU |
| 分类号 |
A61K;C07D401/12;C07D401/14;C07D403/12;C07D403/14 |
主分类号 |
A61K |
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