发明名称 |
VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME |
摘要 |
<p>Compositions comprising isolated RANTES protein and/or a nucleic acid molecule that encodes RANTES protein in combination with isolated IL-8 protein and/or a nucleic acid molecule that encodes IL-8 protein and optionally further comprising an immunogen and/or a nucleic acid molecule that encodes an immunogen are disclosed. Methods of inducing an immune response in an individual against an immunogen comprising administering to the individual isolated RANTES protein and/or a nucleic acid molecule that encodes RANTES protein in combination with isolated IL-8 protein and/or a nucleic acid molecule that encodes IL-8 protein and additionally a target protein and/or a nucleic acid molecule that encodes a target protein are disclosed. Methods of modulating an individual's immune system comprising administering to the individual isolated RANTES protein and/or a nucleic acid molecule that encodes RANTES protein in combination with isolated IL-8 protein and/or a nucleic acid molecule that encodes IL-8 protein are also disclosed. In addition, recombinant vaccines, live attenuated pathogens comprising a nucleotide sequence that encodes IL-8 and a nucleotide sequence that encodes RANTES and methods of the same are disclosed.</p> |
申请公布号 |
EP1280406(A4) |
申请公布日期 |
2005.03.30 |
申请号 |
EP20010935500 |
申请日期 |
2001.05.14 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
WEINER, DAVID, B.;SIN, JEONG-IM |
分类号 |
C12N15/09;A61K38/19;A61K39/12;A61K39/245;A61K39/39;C12N7/04;(IPC1-7):A01N37/18;A61K45/00;A61K38/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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