A syringe for accurately metering small volumes of fluid samples is provided with dual resolution capabilities. The syringe permits the aspiration of a tiny sample and also the dilution of a tiny sample with a much larger volume of reagent with the same syringe. The syringe also allows the aspiration of a minute fluid sample and the touchless transfer off the fluid sample from the tip of the syringe. The present invention allows the aspiration resolution to differ from the dispensing resolution. The dual resolution capabilities also permits the present invention to be implemented into existing conventional syringe drive system. The syringe may include a housing, a piston within the housing, and a plunger extending from the housing. A chamber is formed in the housing between the plunger and a sealing means and between the piston and the inner surface of the housing. The chamber may further include first and second portions, where the volume change of the fluid in the first and second portions corresponds to the dual resolution capabilities.
