发明名称 ANTI-BACTERIAL COMPOSITION, ESPECIALLY FOR CONTROLLING GRAM-NEGATIVE BACTERIA, COMPRISING A PEPTIDE AND AN ADVANTAGEOUSLY HYDROPHOBIC ANTI-BACTERIAL AGENT
摘要 The invention relates to an anti-bacterial composition, especially for controlling gram-negative bacteria, containing a combination of: a) at least one peptide of between 10 and 25 amino acid residues comprising: i) two positively charged domains with a neutral pH consisting of between 3 and 9 amino acid residues, at least two thirds thereof being cationic amino acids, ii) a group of two to three non-cationic amino acid residues located between said positively charged domains, iii) a group of between 0 and 10, preferably between 0 and 5, amino acid residues selected from the group comprising non-hydrophobic amino acids and positively charged amino acids, located at one of the terminal ends N or C of the peptide, a positively charged amino acid residue, however, not being directly adjacent to the positively charged domains; and b) at least one anti-bacterial compound.
申请公布号 WO2005018650(A2) 申请公布日期 2005.03.03
申请号 WO2004FR02142 申请日期 2004.08.13
申请人 DIATOS;ARRANZ, VALERIE 发明人 ARRANZ, VALERIE
分类号 A61K31/70;A61K31/7048;A61K38/03;A61K38/08;A61K38/10;A61K38/16;A61K45/00;A61K45/06;A61K48/00;C07K14/00;C12N1/15;C12N5/20;C12N15/11 主分类号 A61K31/70
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