| 摘要 |
<p>The submitted invention refers to the compounds with the formula (I): in which n stands for a whole number from 0 to 3, W group with the formula (i), (ii) or (iii): in which R stands for hydrogen or C1-4-alkyl, X stands for -O-, -S-, -NH- or -CH2-, Y stands for oxygen or sulphur and the chiral centre is represented in the formula (i) or (ii) in its (S) or (R) form or their mixture is in any ratios; and Z stands for a group with the formula (iv), (v) or (vi): in which R1 and R2 are independently chosen from C1-4alkyl and R3 stands for hydrogen or C1- 4alkyl; it also refers to their salts, solvates and physiologically functional derivatives. The invention also refers to the procedures for their preparation, to the medicines that contain them and to their use as therapeutic means, particularly in the migraine prophylaxis and treatment. (I) (i) (ii) (iii) (iv) (v) (vi)</p> |
