发明名称 |
COMPOSITION COMPRISING TESTOSTERONE UNDECANOATE AND CASTOR OIL |
摘要 |
FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a pharmaceutical composition as a capsule for oral administration that comprises testosterone undecanoate as an active component dissolved in pharmaceutically acceptable liquid carrier wherein liquid carrier involves at least 50 wt.-% of castor oil. Using castor oil as a liquid carrier in combination with testosterone undecanoate as androgen provides preparing a solution that can contain about 200-250 mg of testosterone undecanoate/ml that represents the new achievement for testosterone solution for oral administration. Solution can contain lipophilic surface-active substance, such as lauryl glycol also. The composition shows good absorption in human body and elicits higher activity as compared with the known composition of undecanoate. ^ EFFECT: improved and valuable properties of composition. ^ 7 cl, 1 ex |
申请公布号 |
RU2246296(C2) |
申请公布日期 |
2005.02.20 |
申请号 |
RU20010129362 |
申请日期 |
2000.03.27 |
申请人 |
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发明人 |
NEJS DE KHENRIK;CHANDLER S'JUZN;PERRI EHLIZABET EHNN;FERDINANDO DZHOZEFIN DZHOAN KRISTIN |
分类号 |
A61K9/48;A61K31/568;A61K47/12;A61K47/44;A61P5/26;A61P15/16;A61P43/00 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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