发明名称 |
Adjuvant for vaccine composition |
摘要 |
An amphipathic compound including a sterol-derived lipophilic grouping bound to a cationic grouping for use as an adjuvant in the delivery of a vaccine composition. In a particular embodiment, the lipophilic grouping is a cholesterol derivative and the cationic grouping is a quaternary ammonium or a protonatable amine. A vaccine composition including one or more antigens with at least one amphipathic compound having a sterol-derived lipophilic grouping bound to a cationic grouping, is also disclosed.
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申请公布号 |
US2005002952(A1) |
申请公布日期 |
2005.01.06 |
申请号 |
US20040834616 |
申请日期 |
2004.04.29 |
申请人 |
AVENTIS PASTEUR SA |
发明人 |
HAENSLER JEAN;TRANNOY EMMANUELLE;RONCO JORGE |
分类号 |
A61K47/28;A61K9/00;A61K9/127;A61K39/145;A61K39/39;A61K47/18;A61P31/12;(IPC1-7):A61K39/00;A61K31/56 |
主分类号 |
A61K47/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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