COMPOSITIONS AND METHODS FOR TREATING ATHEROSCLEROSIS
摘要
Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
申请公布号
WO2004111084(A2)
申请公布日期
2004.12.23
申请号
WO2004CA00846
申请日期
2004.06.11
申请人
QUEEN'S UNIVERSITY AT KINGSTON;KISILEVSKY, ROBERT;TAM, SHUI-PANG;ANCSIN, JOHN, B.;JIA, ZONGCHAO