摘要 |
<p>A method of readily and speedily detecting or screening a specimen derived from individuals suspected of infection with COPD by measuring the expression level of gene coding for protein belonging to SCGB family, for example, UGRP2; and a kit with which the method can be effectively carried out. In particular, a method of detecting or screening a specimen derived from individuals suspected of infection with chronic obstructive pulmonary disease, comprising the step of measuring the expression level of gene coding for protein belonging to Secretoglobin family in each of a test sample derived from test subject individuals and a control sample derived from normal individuals, wherein when the expression level in the test sample is higher than that in the control sample, this provides an index expressing that the test sample is one derived from individuals suspected of infection with chronic obstructive pulmonary disease. There is further provided a kit for detection or screening to be used in the above method, comprising a nucleic acid capable of detecting a nucleic acid coding for protein belonging to Secretoglobin family.</p> |
申请人 |
SHIONOGI & CO., LTD.;SONODA, HIKARU;HORI, YOZO;ISHIZAKI, JUN;HIGASHINO, KEN-ICHI;GAHARA, YOSHINARI;OTA, HIDEKI |
发明人 |
SONODA, HIKARU;HORI, YOZO;ISHIZAKI, JUN;HIGASHINO, KEN-ICHI;GAHARA, YOSHINARI;OTA, HIDEKI |