| 发明名称 |
High affinity vascular endothelial growth factor(VEGF) receptor nucleic acid ligands and inhibitors |
| 摘要 |
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to a VEGF receptor. Included in the invention are specific RNA ligands to a VEGF receptor identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of a VEGF receptor with VEGF.
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| 申请公布号 |
US2004224915(A1) |
申请公布日期 |
2004.11.11 |
| 申请号 |
US20040862084 |
申请日期 |
2004.06.04 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
JANJIC NEBOJSA;GOLD LARRY |
| 分类号 |
G01N33/50;A61K38/00;C07H21/00;C12N15/09;C12N15/113;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/68;(IPC1-7):A61K48/00 |
主分类号 |
G01N33/50 |
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