MONOCLONAL ANTIBODY AGAINST RESTON EBOLA VIRUS AND METHOD FOR DETECTING RESTON EBOLA VIRUS USING THE SAME

摘要

PROBLEM TO BE SOLVED: To obtain a monoclonal antibody specific to Reston Ebola virus and to provide a method for differentiating and diagnosing Reston Ebola virus using the antibody.

SOLUTION: The monoclonal antibody is specific to Reston Ebola virus, especially the monoclonal antibody recognizes an epitope composed of a region of an amino acid sequence specific to the virus among nucleoproteins that Reston Ebola virus has. The monoclonal antibody recognizes an epitope composed of a region of four or more of amino acid residues of sequence DPDIGQSK of a specific region in amino acid sequences among nucleoproteins that Reston Ebola virus has. The method for differentiating and diagnosing Reston Ebola virus by the antigen-catching ELISA (enzymelinked immunosorbent assay) process comprises using the monoclonal antibody specific to Reston Ebola virus.

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