发明名称 METHODS OF INDUCING OR ENHANCING CARTILAGE REPAIR
摘要 The invention relates to methods of enhancing repair of a cartilage and/or inducing formation of a cartilage by administering a cell which expresses a factor of the T-box family, which includes inter-alia the brachyury. In another embodiment, the invention relates to an engineered cell, which is transfected with a vector comprising a nucleic acid sequence encoding a factor of the T-box family, thereby expressing a factor of the T-box family. In another embodiment, the invention relates to compositions comprising a vector which comprises a nucleic acid sequence encoding a factor of the T-box family and in another embodiment the composition comprising cell which expresses a factor of the T-box family, which includes inter-alia the brachyury.
申请公布号 WO2004045493(A3) 申请公布日期 2004.11.04
申请号 WO2003IL00976 申请日期 2003.11.18
申请人 YISSUM RES DEV CO;GBF GES FUR BIOTECHNOLOGISHE F;GAZIT DAN;ZILBERMAN YORAM;TURGEMAN GADI;PELLED GADI;GROSS GERHARD;HOFFMANN ANDREA 发明人 GAZIT DAN;ZILBERMAN YORAM;TURGEMAN GADI;PELLED GADI;GROSS GERHARD;HOFFMANN ANDREA
分类号 A61K35/12;C12N5/077 主分类号 A61K35/12
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