USE OF B7-H3 AS AN IMMUNOREGULATORY AGENT

摘要

The present disclosure relates to the fields of immunology and clinical immunology, and more particularly to the use of B7-family ligands and agonis ts and antagonists thereof in modulation of immune response. The invention provides methods for modulation of lymphocyte activation involving the use o f B7-H3, including B7-H3 VC and B7-H3 VCVC, and related molecules such as, for example, antibodies and nucleic acids.