Pseudotyped retroviruses having viral glycoproteins with modified O glycosylation regions are provided. Also provided are methods for making the pseudotyped retroviruses of the present invention and for using the pseudotyped retroviruses for transduction of target cells. Cells for stably producing the pseudotyped retroviruses or the present invention are also provided.
申请公布号
WO03102219(A3)
申请公布日期
2004.10.21
申请号
WO2003US17577
申请日期
2003.06.04
申请人
PURDUE RESEARCH FOUNDATION;CENTERS FOR DISEASE CONTROL AND PREVENTION;SANDERS, DAVID, A.;JEFFERS, SCOTT, A.;SANCHEZ, ANTHONY
发明人
SANDERS, DAVID, A.;JEFFERS, SCOTT, A.;SANCHEZ, ANTHONY