发明名称 |
Sustained release micropellets and process for producing the same |
摘要 |
Sustained release micropellets showing a stable controlled-release of a drug without being affected by the changes in pH value etc., characterized by being produced by coating core particles with a layer containing a water-soluble drug and further forming a film layer containing a water-insoluble polymer compound and a plasticizer on the thus obtained particles, locating a water-soluble filler layer between the water soluble drug-containing layer and the film layer, and having an average particle size of 300 mum or less; medicinal compositions containing these micropellets; and a process for producing the same.
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申请公布号 |
US2004208930(A1) |
申请公布日期 |
2004.10.21 |
申请号 |
US20040486898 |
申请日期 |
2004.02.17 |
申请人 |
YONEDA FUMIO;HAMANO FUMIYA;KITANO EISAKU;HOSONO TETSUYA |
发明人 |
YONEDA FUMIO;HAMANO FUMIYA;KITANO EISAKU;HOSONO TETSUYA |
分类号 |
A61K9/00;A61K9/26;A61K9/50;A61K9/52;A61K31/485;A61K47/38;(IPC1-7):A61K9/26 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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