发明名称 |
TRANSEPITHELIALER TRANSPORT VON MOLEKULARSPEZIEN |
摘要 |
There is disclosed a synthetic cross-linker protein capable of binding a molecule or macromolecular species to a transcytosis receptor for transport of the molecule or macromolecule species across a mucous membrane, said cross-linker protein comprising a first binding region capable of binding selectively to a site on the said molecule or macromolecular species to be transported and a second binding region capable of binding selectively to a site on said receptor, wherein the first binding region is the antigen-binding site of a first antibody molecule having specificity for an antigenic site on said molecule or macromolecular species to be transported and the second binding region is the antigen-binding site of a second antibody molecule which has specificity for an antigenic site on the said transcytosis receptor. |
申请公布号 |
AT277951(T) |
申请公布日期 |
2004.10.15 |
申请号 |
AT19960915101T |
申请日期 |
1996.05.13 |
申请人 |
NATIONAL BLOOD AUTHORITY |
发明人 |
GILMOUR, JACQUELINE ELIZABETH MARY;STINCHCOMBE HILL;UNSWORTH, DAVID JOSEPH |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P37/00;C07K16/18;C07K16/42;C12P21/08;(IPC1-7):C07K16/18 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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