发明名称 |
Inhibitors of cathepsin S |
摘要 |
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme (e.g., cathespin K). The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
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申请公布号 |
US2004198780(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
US20040807612 |
申请日期 |
2004.03.23 |
申请人 |
IRM LLC |
发明人 |
LIU HONG;TULLY DAVID;EPPLE ROBERT;BURSULAYA BADRY;WILLIAMS JENNIFER;CHATTERJEE ARNAB;HARRIS JENNIFER LESLIE;LI JUN |
分类号 |
A61K;C07C237/14;C07C237/20;C07C255/57;C07C275/28;C07C275/30;C07C275/42;C07D213/56;C07D213/64;C07D231/12;C07D237/24;C07D239/52;C07D277/30;C07D277/56;C07D307/38;C07D307/40;C07D307/68;C07D333/20;C07D333/38;(IPC1-7):C07D333/20 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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