VECTOR FOR GENE THERAPY AND METHOD OF QUANTIFYING TARGET PROTEIN IN MAMMAL OR CULTURED CELLS WITH THE ADMINISTRATION OF THE VECTOR FOR GENE THERAPHY

摘要

A vector for gene therapy by which the concentration of a target protein in blood under the gene therapy can be monitored at an elevated sensitivity and in which a labeled peptide has no physiological effect and shows no immunogenicity in many animals. This vector for gene therapy has a structure wherein a nucleic acid encoding a fused protein of the C-terminal side 19-29 amino acid peptide region of glucagon with a target protein region to be produced in vivo is integrated into an expression vector for mammalian cells.