发明名称 |
СПОСОБЫ ДОСТАВКИ ЛЕКАРСТВА В ГЕПАТОЦИТЫ И ЛЕЧЕНИЕ ИНФЕКЦИЙ ФЛАВИВИРУСОВ |
摘要 |
A method of delivering a drug to a hepatocyte includes a step in which a carboxamidine group-containing compound is provided to a hepatocyte having a transporter that transports the compound across the plasma membrane of the hepatocyte, wherein the transport of the compound is substantially not inhibited by ribavirin. Further contemplated methods include a method of inhibiting growth of a virus of a family of flaviviridae in a cell containing system, in which contemplated compounds are presented to a cell in the cell containing system. |
申请公布号 |
RU2003102607(A) |
申请公布日期 |
2004.07.27 |
申请号 |
RU20030102607 |
申请日期 |
2001.08.21 |
申请人 |
Рибафарм Инк. (US) |
发明人 |
ЛО Джонсон (US);ХОНГ Жи (US) |
分类号 |
C12N7/06;A61K31/155;A61K31/41;A61K31/7056;A61P1/16;A61P31/12;A61P31/14;A61P35/00;C07H19/056 |
主分类号 |
C12N7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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