发明名称 |
USE OF COLLAGENASE TO FACILITATE GUIDE WIRE CROSSING IN CHRONIC ARTERIAL OCCLUSIONS |
摘要 |
The use of a collagenase containing formulation for degrading collagen within an occlusive atherosclerotic plaque in a chronic fibrotic occlusion, chronically occluded animal tube or cavity. A medical-related apparatus is provided comprising a medical-related device having provided thereto a therapeutic amount of a collagen degrading composition comprising a proteiolytic enzyme containing formulation A method is provided for treating chronically occluded animal tubes and cavities by administering a therapeutic effective amount of a proteolytic enzyme-containing formulation adjacent to an occluding atherosclerotic plaque, waiting for a pre-angioplasty waiting period, followed by crossing the plaque with an angioplasty guide wire. |
申请公布号 |
EP1438065(A2) |
申请公布日期 |
2004.07.21 |
申请号 |
EP20020764443 |
申请日期 |
2002.10.01 |
申请人 |
MATRIZYME PHARMA CORPORATION |
发明人 |
BRADLEY H. STRAUSS |
分类号 |
A01K67/027;A61K38/48;A61B17/12;A61D1/00;A61D7/00;A61K38/46;A61K38/51;A61L29/16;A61L31/16;A61P7/02;A61P9/10;(IPC1-7):A61K38/48 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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