| 摘要 |
FIELD: organic chemistry, chemical technology. ^ SUBSTANCE: invention relates to the improved method for preparing delta-9-tetrahydrocannabinol esters of the formula (I): ^ ^ wherein R represents the group of the formula: ^ ^ wherein R' represents alkyl comprising carboxyl group. Method involves interaction of delta-9-tetrahydrocannabinol with halide anhydride or acid anhydride having R as a residual group in the presence of 4-amino-substituted pyridine of the formula: ^ ^ wherein each R1 and R2 represents independently hydrogen atom, optionally substituted lower alkyl; or R1 and R2 can form in common 5- or 6-membered heterocyclic ring. ^ EFFECT: improved preparing method, enhanced yield. ^ 10 cl, 13 ex |
