发明名称 |
CATALYTIC ANTIOXIDANTS AND METHODS OF USE |
摘要 |
The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substates for enzymes of the methionine sulfoxide reductase (Msr) class. Some embodiments of the catalytic antioxidant compounds are derived from drugs with anti-inflammatory activity due to inhibition of cyclooxygenase enzymes. |
申请公布号 |
WO2004047772(A3) |
申请公布日期 |
2004.07.15 |
申请号 |
WO2003US38817 |
申请日期 |
2003.11.26 |
申请人 |
FLORIDA ATLANTIC UNIVERSITY;HOSPITAL FOR SPECIAL SURGERY |
发明人 |
WEISSBACH, HERBERT;BROT, NATHAN |
分类号 |
A61K38/00;C07C317/44;C07C317/50;C07C323/59;C07C323/60;C07D209/26;C07D307/58;C07K5/06;C07K5/065 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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