BACTERIOPHAGE-ENCODED ANTIBACTERIAL ENZYME FOR THE TREATMENT AND PREVENTION OF GINGIVITIS AND ROOT SURFACE CARIES
摘要
A method and composition for the treatment and prevention of gingivitis and root surface caries using Actinomyces naeslundii bacteriophage Av-1 encoded anti-bacterial enzyme (Av-1 lysin) to remove and inhibit establishment of cariogenic and pathogenic bacteria in the oral cavity is disclosed, along with the amino acid sequence of the enzyme used therein and the isolated DNA molecule encoding the same.
申请公布号
WO2004058088(A2)
申请公布日期
2004.07.15
申请号
WO2003US41158
申请日期
2003.12.23
申请人
UNIVERSITY OF MARYLAND, BALTIMORE;DELISLE, ALLAN, L.;BARCAK, GERARD, J.;GUO, MING