Thiazole compounds useful as inhibitors of protein kinase

摘要

The present invention provides a compound of formula I:or a pharmaceutically acceptable derivative thereof, wherein Ar<1 >is phenyl and R<1 >is as defined in the specification. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3, Aurora2, and Syk mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.