发明名称 |
Metalloporphyrins and their uses as radiosensitizers for radiation therapy |
摘要 |
The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages having the structurewhich selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. The present invention also covers methods for using these radiosensitizers in tumor imaging and cancer treatment.
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申请公布号 |
US6759403(B2) |
申请公布日期 |
2004.07.06 |
申请号 |
US20020117010 |
申请日期 |
2002.04.05 |
申请人 |
BROOKHAVEN SCIENCE ASSOCIATES, LLC |
发明人 |
MIURA MICHIKO;SLATKIN DANIEL N. |
分类号 |
A61K31/409;A61K41/00;A61K51/04;A61P35/00;C07D487/22;(IPC1-7):C07D487/22 |
主分类号 |
A61K31/409 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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