| 摘要 |
The present invention is directed to the production and use of custom tailored, bacterial enzyme mixtures or components thereof for degrading biofilms in both industrial and therapeutic applications. The industrial applications include but are not limited to the use biofilm-degrading, multiple specificity, hydrolytic enzyme mixtures for removing or preventing the formation of biofilms in water cooling towers, industrial process piping, heat exchangers, in food processing or food preparation, in potable water systems, reservoirs, swimming pools, or related sanitary water systems, and on membranes such as those used for desalinization, industrial processes, or related applications. The therapeutic applications include but are not limited to the use of therapeutically-useful, multiple-specificity, hydrolytic enzyme mixtures for the prevention or treatment of dental caries, periodontal disease, cystic fibrosis or the complications or symptoms of cystic fibrosis, removal of biofilms from contact lenses, and diseases or complications associated with biofilm formation on implantable medical devices such as cardiovascular devices.
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