| 发明名称 |
Targeted protein degradation vehicles (tpdvs), nucleic acid constructs encoding them and their use |
| 摘要 |
<p>Targeted protein degradation vehicles are disclosed which comprise at least an affinity domain which binds to a specific target, a delivery domain which delivers the vehicle into a cell and a functional domain which degrades selectively a target protein.</p> |
| 申请公布号 |
EP1426055(A1) |
申请公布日期 |
2004.06.09 |
| 申请号 |
EP20020026850 |
申请日期 |
2002.11.29 |
| 申请人 |
CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG-SPEYER-HAUS |
发明人 |
BUERGER, CLAUDIA;GRONER, BERND, PROF.DR.;NAGEL-WOLFRUM, KERSTIN;KUNZ, CHRISTIAN;WITTIG, ILKA |
| 分类号 |
A61K38/00;A61K38/17;A61K47/48;A61P9/00;A61P17/06;A61P25/28;A61P29/00;A61P35/00;C07K14/47;C07K14/485;C12N15/09;C12N15/12;C12N15/62;C12N15/63;(IPC1-7):A61K38/17 |
主分类号 |
A61K38/00 |
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