Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof

摘要

There is provided an aminophenoxyacetic acid derivative of the following formula (I): wherein, R<1>, R<2>, R<3 >and R<4 >are, independent from each other, alkoxy group, alkyl group or aryl group, etc.; E<1 >and E<2 >are oxygen atom, sulfur atom, etc.; n is 0 to 5; X and Y are alkylene group, cycloalkylen group, or alkenylen group; Q is pheny group which may be substituted or benzoyl group, etc, or a pharmaceutically acceptable salt thereof. These compounds have neuroprotective effects by inducing calbindin D28Kd, one of Ca<2+>-binding proteins.