发明名称 |
NEW PROCESS FOR THE SYNTHESIS OF HIGH PURITY 3,5-DIAMINO-6-(2, 3-DICHLOROPHENYL)-1,2,4-TRIAZINE |
摘要 |
<p>The present invention relates to a new process for the synthesis of high purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine of formula (I) using 2,3-dichlorobenzoyl cyanide and an aminoguanidine salt as starting materials. 2,3-dichlorobenzoyl cyanide is reacted with 1-2 mol equivalent of aminoguanidine salt in 3-6 mol equivalent of methanesulfonic acid, then the obtained adduct of formula (IV) is transformed without isolation into the product with magnesium oxide. In given case the obtained crude product can be recrystallized from a proper organic solvent.</p> |
申请公布号 |
WO2004026845(A1) |
申请公布日期 |
2004.04.01 |
申请号 |
WO2003HU00072 |
申请日期 |
2003.09.18 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT.;NEU, JOZSEF;GIZUR, TIBOR;TOERLEY, JOZSEF;CSABAI, JANOS;VEGH, FERENC;KALVIN, PETER;TARKANYI, GABOR |
发明人 |
NEU, JOZSEF;GIZUR, TIBOR;TOERLEY, JOZSEF;CSABAI, JANOS;VEGH, FERENC;KALVIN, PETER;TARKANYI, GABOR |
分类号 |
C07C281/16;C07D253/075;(IPC1-7):C07D253/06 |
主分类号 |
C07C281/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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