发明名称 HIGH LEVEL EXPRESSION OF PROTEIN IN YEAST
摘要 <P>PROBLEM TO BE SOLVED: To provide a method and material for increasing yield of a foreign protein. <P>SOLUTION: This invention provides a method of expressing a non-yeast protein under the control of ADH (alcohol dehydrogenase) 2 control sequence in an yeast host having enhanced ADRI expression, and a transformed yeast host. Provided is a transformed yeast which has an expression cassette incorporated in a genome containing a coding sequence of ADRI under the control of a transcription initiation sequence and a transcription termination sequence recognized by the yeast and the transcription initiation sequence is a promotor except an ADR1 promotor. <P>COPYRIGHT: (C)2004,JPO
申请公布号 JP2004081222(A) 申请公布日期 2004.03.18
申请号 JP20030412625 申请日期 2003.12.10
申请人 CHIRON CORP 发明人 SHUSTER JEFFREY R
分类号 C12N1/19;C07K14/50;C12N15/09;C12N15/81;C12N15/90;C12P21/00;C12R1/865 主分类号 C12N1/19
代理机构 代理人
主权项
地址