Methods for monitoring and prognosis of disease course of gastrointestinal tumors

摘要

The present invention provides a method for diagnosis, monitoring and prognosticating the disease course of gastrointestinal tumors, comprising determining the level of a cyclin dependent kinase inhibitor (CKI) in a sample and diagnosing the disease and/or recurrence of the disease or prognosticating the disease course from the level of said CKI in the examined tumor cells. Furthermore the present invention provides a method for tailoring a suitable therapy for gastrointestinal tumors. Another aspect of the present invention are test kits for research and diagnostic purposes.