| 摘要 |
FIELD: organic chemistry, cosmetology. SUBSTANCE: the present innovation deals with new compounds of 2-hydroxy-2 methyl- N-(4-X-3- (trifluoromethyl)phenyl)-3- perfluoracylamino)propionamide, where X means nitro, cyano or halogen, and perfluoracylamino contains 2-3 carbon atoms and 0-1 hydrogen atom. The mentioned compounds specifically inhibit and/or eliminate receptors of head skin androgens and, thus, could be applied as cosmetic substance in case of cutaneous disorders caused by excess of androgens, such as hair fall out, hirsutism, acne and androgenic alopecia. EFFECT: higher efficiency of application. 11 cl, 11 ex, 4 tbl
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