Genetically-determined variation in expression levels is an important component of human diversity and has significant implications for normal and abnormal human physiology. Using this genetically determined variation one can identify disease risk factors in individuals. One can associate such variations with birth defects, diseases, and non-disease traits. Such variations can be associated with susceptibility or resistance to the effects of drugs or other therapeutic interventions.
申请公布号
WO03104398(A3)
申请公布日期
2004.02.12
申请号
WO2003US17262
申请日期
2003.06.04
申请人
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE;YAN, HAI;KINZLER, KENNETH, W.;VOGELSTEIN, BERT