| 发明名称 |
Triazospiro compounds having nociceptin receptor affinity |
| 摘要 |
Disclosed are compounds of the formula (I)wherein A, R1, R2, R3, R4 and X1 are as disclosed herein. The compounds have affinity for the ORL1 receptor and are useful in the treatment of chronic and acute pain.
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| 申请公布号 |
US6686370(B2) |
申请公布日期 |
2004.02.03 |
| 申请号 |
US20000730938 |
申请日期 |
2000.12.06 |
| 申请人 |
EURO-CELTIQUE S.A. |
发明人 |
KYLE DONALD;GOEHRING R. RICHARD |
| 分类号 |
A61K31/00;A61K31/438;A61K31/445;A61K31/4709;A61K31/496;A61P13/00;A61P23/00;A61P25/04;A61P29/00;A61P39/00;A61P43/00;C07D471/10;(IPC1-7):A61K31/474;C07D221/20 |
主分类号 |
A61K31/00 |
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