POLYALKYLENE GLYCOLS, DERIVATIVES AND CONJUGATES THEREOF IN PARTICULATE FORM

摘要

A polyalkylene glycol (PAG) - preferably a polyethylene glycol - or a derivative or conjugate thereof, in particulate form, having a residual solvent content of 200 ppm or less and a volume mean particle diameter of 25 µm or less. Also methods for forming particulate products containing PAGs or derivatives or conjugates thereof, in particular by carrying out a GAS process - preferably a Nektar<TM >SCF process - on a solution or suspension of a target substance but using as the anti-solvent fluid a compressed fluid which at the point of its contact with the solution or suspension is at a temperature of 25°C or below.