Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
申请公布号
US6683173(B2)
申请公布日期
2004.01.27
申请号
US20010032307
申请日期
2001.12.21
申请人
EPOCH BIOSCIENCES INC
发明人
DEMPCY ROBERT O;LOKHOV SERGEY G;KUTYAVIN IGOR V;VERMEULEN NICOLAAS M J